Multicentric Bowen disease in linear porokeratosis.
نویسندگان
چکیده
Linear porokeratosis is a genodermatosis, caused by a clonal proliferation of keratinocytes along the lines of Blaschko. This type of porokeratosis is particularly susceptible to malignant degeneration e.g. to Bowen disease, a squamous cell carcinoma (SCC) in situ with the potential for significant lateral spread. Here we report a case of linear porokeratosis on the left leg of a 56-year-old man, complicated with two lesions of multicentric Bowen disease.
منابع مشابه
Multicentric squamous cell carcinoma over lesions of porokeratosis palmaris et plantaris disseminata and giant porokeratosis.
Porokeratosis is a specific disorder of keratinization that has five clinical types and shows a characteristic 'cornoid lamella' on histopathology. Malignant degeneration has been described in all forms of porokeratosis. To the best of our knowledge, this is the first Indian report of multicentric squamous cell carcinoma complicating porokeratosis.
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Porokeratosis (PK) is an uncommon disorder of epidermal keratinization characterized by annular plaques with an atrophic center surrounded by a raised, keratotic wall, with unknown aetiology and an unpredictable outcome. It has several clinical forms including porokeratosis of Mibelli, giant porokeratosis, linear porokeratosis, disseminated superficial actinic porokeratosis, palmoplantar ...
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Sir, Six main clinical forms of porokeratosis are recognized: classical porokeratosis or porokeratosis of Mibelli, punctate palmoplantar porokeratosis, linear porokeratosis (LP), disseminated superficial porokeratosis, disseminated superficial actinic porokeratosis (DSAP), and disseminated palmoplantar porokeratosis (1). The coexistence of more than one form in a single individual is infrequent...
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ورودعنوان ژورنال:
- European journal of dermatology : EJD
دوره 17 5 شماره
صفحات -
تاریخ انتشار 2007